Taiwan's vaccine industry faces significant challenges, from the H1N1 vaccine by Kuo-Kuang Biotechnology to the COVID-19 vaccine by High-End Biotech. Despite starting late and struggling with domestic confidence, the industry is modernizing. The "Taiwan Vaccine Industry Association" was established on August 27, 2021, by experts and nine vaccine-related companies to document the industry's history through the book History of Vaccine Industry in Taiwan and to provide insights for the future.